Multicentric validation of a model based on phenotypic features to predict microsatellite instability in colorectal adenocarcinoma

R ROMAN1, M VERDU1,3, A VIDAL3,5, M CALVO4, X SANJUAN5, M JIMENO6, A SALAS7, J AUTONELL8, I TRIAS9, N RODON1, M GONZALEZ1, B GARCIA1 and X PUIG1,2,3.

1BIOPAT.Biopatologia Molecular, Barcelona, Spain; 2Hospital de Barcelona, Barcelona, Spain; 3Histopat Laboratoris, Barcelona, Spain; 4Statistics Department, Universitat de Barcelona, Barcelona, Spain; 5Hospital Universitari de Bellvitge, Barcelona, Spain; 6Hospital del Mar, […]

2009-03-23T17:17:26+00:00

Colo-rectal micropapillary carcinoma: a clinicopathological and molecular study of 27 cases

Ruth Roman1, Montse Verdú 1,3, August Vidal 1,3, Miquel Calvo 4, Natalia Rodón1, Beatriz García1, Marta González1 and Xavier Puig1,2,3.

1BIOPAT. Biopatologia Molecular, SL, Grup Assistencia; 2Hospital de Barcelona SCIAS, Grup Assistència; 3Histopat Laboratoris and 4Statistics Department, Universitat de Barcelona. Barcelona, Spain.

INTRODUCTION: Invasive micropapillary carcinoma (MC) is associated with frequent lymph node metastasis and adverse clinical […]

2008-05-23T17:13:35+00:00

A population study on the UGT1A1*28 variant associated to Irinotecan tolerance

Roman R,1 Colomer A,1 Erill N,1 Verdú M,2 Ibáñez R,1 Cordon-Cardo C,1 Puig X.1,2

1BIOPAT. Biopatologia Molecular, Grup Assistència & 2HISTOPAT Laboratoris, Barcelona, Catalonia, Spain.

Background: Irinotecan (CPT-11) is currently used as first- or second-line treatment for colorectal cancer, either alone or in combination with 5-fluorouracil based regimens. UDP-glucuronosyltransferase 1A1 (UGT1A1) catalyzes the inactivation of SN-38, the […]

2006-09-23T17:11:42+00:00

Estudio mutacional de BRAF y KRAS en cáncer colorrectal: carcinoma esporádico versus síndrome familiar no asociado a poliposis

A Colomer1, N Erill1, A Vidal1, 2, M Verdú2, R Román1, C. Cordón3, X Puig1,2.

1 BIOPAT. Biopatologia Molecular.  Grup Assistència. Barcelona. 2 Histopat laboratoris, Barcelona. 3 Division of Molecular Pathology, Memorial Sloan-Kettering Cancer Center, New York. 

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X Congreso Nacional de la Sociedad Española de […]

2005-09-01T01:17:23+00:00

La inestabilidad de microsatélites en el cáncer colorrectal puede predecirse en base al fenotipo tumoral

A Colomer1, N Erill1, A Vidal1,2, M Calvo3, R Román1, M Verdú2, C Cordón 4, X Puig 1,2.

1 BIOPAT. Biopatologia Molecular.  Grup Assistència. Barcelona. 2 Histopat laboratoris, Barcelona. 3 Departamento de Estadística de la Universidad de Barcelona. Barcelona.  4 Division of Molecular Pathology, Memorial Sloan-Kettering Cancer Center, New York. 

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XXII […]

2005-09-01T01:12:41+00:00