Highly sensitive real-time PCR for the detection of EGFR mutations in lung adenocarcinoma. Is it worth it?
Rodon Natalia1, Roman Ruth1, Verdu Montse1,3, Garcia Beatriz1, Pujol Merce1 and Puig Xavier1,2,3.
1BIOPAT.Biopatologia Molecular, SL, Grup Assistencia, Barcelona, Spain; 2Hospital de Barcelona, SCIAS, Grup Assistencia, Barcelona, Spain; 3Histopat Laboratoris, Barcelona, Spain.
Background: Mutations involving the epidermal growth factor receptor (EGFR) correlate with responsiveness to tyrosine kinase inhibitors (TKIs), which significantly improves patient survival in lung adenocarcinoma (AC). These mutations are described […]