Genetic alterations of the epidermal growth factor receptor pathway in a series of non-small cell lung cancer characterized by morphology and immunophenotype

Verdú M,1 Colomer A,1 Erill N,1 Roman R,2 Górriz M, 1,2 Ibáñez R,1 Cordon-Cardo C,1 Puig X.1,2

1HISTOPAT Laboratoris, Barcelona, Catalonia, Spain & 2BIOPAT. Biopatologia Molecular, Grup Assistència.

Background: Non-small cell lung cancer (NSCLC) is classified in two main categories: adenocarcinoma (AC), which includes bronchioloalveolar carcinoma (BAC), and squamous cell carcinoma (SCC). Activating mutations and increased copy […]


Epidermal growth factor receptor in non small cell lung cancer: Gene copy number and mutational study

Colomer A1, Erill N1, Verdú M2, Román R 1, Górriz M2, Ibáñez R1, Menoyo A1, Cordon-Cardo C3, Puig X 1,2.

1BIOPAT, Grup Assistència, 2HISTOPAT Laboratoris, Barcelona, Spain; and 3Division of Molecular Pathology, Memorial Sloan-Kettering Cancer Center, New York, United States.

Background: Activating mutations of the EGFR gene were identified in tumors from patients with non small cell […]


Carcinoma de pulmón de células no pequeñas: caracterización inmunohistoquímica y estudio molecular del gen del receptor de EGF

N Erill1, A Colomer1, M Verdú2, R Román1, A Menoyo1, Carlos Cordón-Cardó1,2,3, Xavier Puig1,2.

1 BIOPAT. Biopatologia Molecular.  Grup Assistència. Barcelona. 2 Histopat laboratoris, Barcelona. 3 Division of Molecular Pathology, Memorial Sloan-Kettering Cancer Center, New York. 

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Póster presentado en:

XXII Congreso de la Sociedad Española de Anatomía Patológica 2005


Diagnostic sub-classification of non-small cell lung cancer: Importance in clinical therapeutics and prognostication

M. J. Donovan, A. Kotsianti, A. Colomer, M. Verdú, M. Clayton, H. Pang, S. Hamann, C. Cordón-Cardó, X. Puig.

Background: The association of EGFR mutations with bronchoalveolar carcinoma (BAC) / non-small cell lung cancer (NSCLC) and the therapeutic and prognostic variability reported for lung cancer has reinforced the need for more accurate NSCLC sub-classification. The present […]